邀请人：李玉同 研究员（Tel：82648014）

主办单位：中国科学院光物理重点实验室

摘要：

Laser-driven protons are promising sources for cancer radiotherapy because of their unique advantages such as high instantaneous flux, small source size and broad energy spread. Recently, FLASH radiotherapy based on laser-driven protons, which delivers dose to a tumor with an ultra-high dose rate, has demonstrated reduced normal-tissue toxicity while preserving tumor-control efficacy. By utilizing PW fs lasers, the generation of protons > 100 MeV has been reported by multiple groups, which further strengthens the feasibility of their clinical use. However, these achievements were mainly achieved in single-shot experiments. For actual implementation of the radiotherapy treatment plan, high-rep and continuous generation of proton beams are essential. In this talk, I will address the critical challenges in high-rep and continuous generation of high-energy protons with PW lasers, and introduce our recent progress towards the development and commissioning of a petawatt-class laser-driven proton acceleration platform at the CLAPA‑II facility. In experiments conducted at 0.1 Hz and 1 PW, the platform consecutively delivered proton pulses with an average proton cutoff energy of 60 ± 5 MeV, and a yield exceeding 10^10 protons per pulse, corresponding to a maximum penetration depth in tissue of approximately 3 cm. These results demonstrate a scalable pathway toward stable proton generation at petawtt-scale laser power, and highlight the potential of laser-proton FLASH radiotherapy for tumours.

简介：

马文君，北京大学博雅特聘教授，国家杰出青年科学基金获得者。长期从事超强激光与物质相互作用及应用研究。开创性地将碳纳米管泡沫靶等先进靶材用于激光驱动的高能离子加速与高亮度X射线产生，多次打破激光离子加速能量记录。近年来致力于发展面向激光质子放疗、先进制程半导体工艺、聚变核能利用等领域的先进粒子与射线源，聚焦其中与靶相关的关键科学与技术问题，促进技术落地。目前担任北京大学副院长，北京激光加速创新中心副主任。